The orphan nuclear receptor LRH-1/NR5a2 critically regulates T cell functions
نویسندگان
چکیده
منابع مشابه
The nuclear receptor LRH-1 critically regulates extra-adrenal glucocorticoid synthesis in the intestine
The nuclear receptor liver receptor homologue-1 (LRH-1, NR5A2) is a crucial transcriptional regulator of many metabolic pathways. In addition, LRH-1 is expressed in intestinal crypt cells where it regulates the epithelial cell renewal and contributes to tumorigenesis through the induction of cell cycle proteins. We have recently identified the intestinal epithelium as an important extra-adrenal...
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ژورنال
عنوان ژورنال: Science Advances
سال: 2019
ISSN: 2375-2548
DOI: 10.1126/sciadv.aav9732